Novo Nordisk

Continue to the
real world evidence update.

Novo Nordisk

Check-in & executive update

Real world evidence update

A snapshot of Alnu Health's growing care network, the patients we support, and the structured signals generated between clinic visits.

1,252patients

+46% since last conversation

46,965meals logged

+134% since last conversation

−5.8 lbaverage weight change

The digital care extension layer

A configurable Patient-Facing Companion and EHR Integration/Clinician Portal, connected through the Alnu Health Platform and built around the way each Healthcare System delivers research-driven care.

9:41
July Expand
Food & Drink
Calories94% of goal
1,214kcal consumed
Remaining79Goal1,293
MacrosEdit Goals0 of 4 met
Patient-Facing CompanionTracks, Learns, Asks
Clinician PortalReviews & Follows Up

Alnu Health at a glance

Growing reach. Real patient activity.

Alnu is live across a multi-state clinic footprint, with a growing production population and substantial partner pipeline.

Clinic network 48

+129% since last conversation

launched clinic locations

Geographic reach 10

states in the declared footprint

Patients 1,252

+46% since last conversation

patients in production

Partner pipeline 7,700

+196% since last conversation

members onboarding at current customers

Current footprint

United States map highlighting California, Colorado, Florida, Georgia, Minnesota, New York, North Dakota, Tennessee, Texas, and Wisconsin.
Active footprint Other states
CACaliforniaCOColorado FLFloridaGAGeorgia MNMinnesotaNYNew York NDNorth DakotaTNTennessee TXTexasWIWisconsin

Scale ahead

28,000

Patients represented under LOI at various clinics.

Patient population

A broad population, centered in midlife.

Demographics reflect active patients who completed onboarding, with response counts shown where data was missing or invalid.

Average age 51.6 years · 1,153 valid responses
Currently taking a GLP-1 36.1% 452 patients

Gender distribution

Four in five patients identify as women

Female79.9% · 922
Male19.6% · 226
Prefer not to say0.3%
Non-binary0.2%

GLP-1 treatment mix

Tirzepatide leads current use.

Tirzepatide74.7%
Semaglutide23.2%
Other2.1%

Experience on therapy

Patients bring nearly a year of GLP-1 experience on average.

11.1 average months of use across 431 valid start dates
Prior medication switch 69 patients self-reporting a switch
Current GLP-1 population 452 36.1% of patients

Meals & patient engagement

Nutrition is the highest-volume daily signal.

Each meal creates structured macro data and, in most cases, immediate nutrition feedback that patients can act on in the moment.

Most common side effects

Overview of adverse events

Based on 741 structured side-effect records.

81.0% reported suppressed appetite
Suppressed appetite81.0%
Food noise61.9%
Constipation27.3%
Acid reflux or heartburn20.9%
Nausea12.3%
Stomach pain or cramping8.5%
Diarrhea3.9%
Fatigue1.8%
Headaches1.8%
Bloating1.3%

What patients ask the coach

Nutrition dominates the conversation.

Themes are determined through privacy-safe, deterministic multi-label classification of 1,983 user-authored questions.

43.6%

Nutrition

The leading broad theme by a wide margin.

7.4%

Injection

Questions about injections, medication, and schedules.

6.1%

Weight

Questions about progress, change, and plateaus.

5.3%

Exercise

Questions on movement, routines, and muscle retention.

0.7%

Side effects

Questions about symptoms and day-to-day management.

Finer-grained topics

The same 1,983 questions, classified into more specific topics when the language is more precise than the broad themes above.

Nutrition & protein27.1%
Medication & dosing4.7%
Exercise4.1%
Hydration1.2%
Cravings & hunger0.9%
Side-effect management0.4%
Weight plateaus0.1%
“How can I get enough protein while eating smaller portions?”
“What should I know about my medication dose and injection schedule?”
“What exercise routine best supports weight loss and muscle retention?”

Structured data captured

Proprietary data generated by the platform

The companion and portal generate longitudinal, real-world evidence across the patient journey, medication use, adherence, engagement, provider workflow, and multi-condition expansion.

01

Longitudinal Patient Journey Data

  • Trajectories of weight, metabolic markers, vitals, and behavioral patterns
  • Real-world response timelines to GLP-1 initiation, titration, and maintenance
  • Long-term adherence patterns and predictors of sustained outcomes
  • Cross-condition interactions as patients evolve into broader chronic care needs
02

Medication Use & Optimization Data

  • Optimal titration patterns by archetype, lifestyle, comorbidities, and demographics
  • Side effect profiles and early predictors of intolerance or discontinuation
  • Personalized dosing pathways driven by agentic AI recommendations
  • Real-world evidence on comparative efficacy of different GLP-1 products
03

Drop-Off, Adherence, and Retention Insights

  • Precise reasons for discontinuation (side effects, cost, access, engagement)
  • Behavioral markers that indicate upcoming dropout
  • Intervention types that most effectively restore adherence
  • Provider behaviors correlated with patient retention
04

Patient Engagement & Behavior Data

  • How patients interact with guidance, coaching, nudges, or AI-driven workflows
  • Patterns in self-reporting, check-ins, and biometric tracking
05

Provider Workflow & Decision-Making Data

  • How clinicians modify AI recommendations across different patient profiles
  • Workflow bottlenecks and variation between care settings
  • Provider acceptance of care pathways and clinical decision support
  • Best-performing care models for outcomes and cost savings
06

Multi-Condition Expansion Data

  • How GLP-1 patterns correlate with diabetes, cardiovascular disease, PCOS, MASH, etc.
  • Early detection signals for emerging chronic conditions
  • Cross-condition outcome models powering expansion of your chronic disease operating system

Wearables & smart scales

Connected devices extend the structured profile between visits.

Alnu is a partner with seca and InBody for clinical-grade body composition. Patients can also connect wearables and home scales — including Oura, WHOOP, Fitbit, Withings, Garmin, and Apple Watch via Apple Health — so activity, sleep, and weight land in the same longitudinal record.

Partner seca

Clinical-grade body composition in clinic.

Partner InBody

Clinical-grade body composition in clinic.

Also connected

01 WelcomeIdentity, baseline measurements, and GLP-1 journey
What brings you to Alnu?
Multi-select, required
Weight loss supportGLP-1 medication trackingNutrition guidanceAccountability & motivationManaging side effectsPersonalized health coachingOther
About you
Name, birthday, current weight, and height are captured as structured text, date, and compound-number fields.
Gender
Single-select, required
MaleFemaleNon-binaryPrefer not to say
Where are you in your GLP-1 journey?
Single-select, required
Currently taking a GLP-1Not taking one, but interestedGeneral health support
02 Medication detailsMedication, dose, start date, weight, and switch history
Current GLP-1 medication
Shown when currently taking
ZepboundMounjaroTirzepatide (compounded)WegovyWegovy (oral)Foundayo / OrforglipronOzempicSemaglutide (compounded)RybelsusSaxendaTrulicityOther
Current dose
Medication-dependent single-select
0.25 mg0.5 mg0.6 mg0.75 mg0.8 mg1 mg1.2 mg1.5 mg1.7 mg1.8 mg2 mg2.4 mg2.5 mg3 mg4 mg4.5 mg5 mg5.5 mg7 mg7.5 mg9 mg10 mg12.5 mg14 mg14.5 mg15 mg17.2 mg25 mgCustom dose
Medication history
Medication start date, approximate GLP-1 starting weight, and whether the patient switched from another GLP-1.
03 Health historyGoals, conditions, activity, restrictions, and pregnancy status
Target weight goal
Single-select with conditional goal weight
Yes, I have a specific goalNo, focused on overall health
Health conditions
Multi-select
NoneType 2 diabetesType 1 diabetesPrediabetesHigh blood pressureHigh cholesterolHeart diseaseThyroid issuesPCOSSleep apneaOther
Daily activity level
Single-select
Mostly sedentaryLightly activeModerately activeVery activeExtremely active
Dietary restrictions or allergies
Multi-select
NoneVegetarianVeganGluten-freeDairy-freeNut allergyShellfish allergyKosherHalalOther
Pregnancy status
Shown for female or non-binary patients
Not applicableNoCurrently pregnantPlanning pregnancyBreastfeedingPrefer not to say
04 Journey detailsInjection schedule, outcomes, motivation, and family history
Injection schedule
Next injection date plus frequency for injectable medications
Once a weekEvery two weeksDaily
Most important outcome
Single-select
Lose weightImprove overall healthHave more energyFeel more confidentLive longer, healthierManage a health conditionOther
Bigger goal or motivation
Optional free-text prompt used to personalize coaching; not included in this aggregate export.
Family health history
Multi-select
NoneDiabetesHeart diseaseObesityThyroid cancer / MEN 2Other
05 Nutrition & lifestyleEating habits, food preferences, sleep, and daily steps
Current eating habits
Single-select
Regular mealsIrregular scheduleGrazing / snackingOften skip mealsIntermittent fasting
Foods to avoid
Optional free-text food preference field; excluded from aggregate reporting.
Sleep quality
Single-select
ExcellentGoodFairPoorVery poor
Average daily steps
Single-select
Don't trackUnder 3,0003,000–5,0005,000–7,0007,000–10,000Over 10,000
+ Additional structured trackingRegistry dates and ongoing side-effect selections
Registry dates
First injection date and GLP-1 journey start date are captured when applicable.
Side-effect selections
Ongoing multi-select logging includes suppressed appetite, food noise, constipation, reflux/heartburn, nausea, stomach pain/cramping, diarrhea, bloating, headaches, fatigue, burping/gas/indigestion, injection-site reaction, overly full after small meals, depression, upper abdominal pain, muscle loss, vomiting, hair loss, and dizziness.

Longitudinal patient journey

Progress becomes visible over time.

Repeated patient activity links baseline context to changes in weight, BMI, medication, nutrition, side effects, and coaching needs.

Average weight change−5.8 lb313 patients with 2+ valid logs
Average loss2.6%patient-level change from starting weight
Average BMI change−1.19recorded longitudinal change
Injection logs642recorded administrations

Medication journey signals

Treatment changes become structured events.

Injection logs reveal dose changes and medication switches while preserving the limits of what recorded administrations can establish.

12 medication switches observed between injection logs
103 dose changes observed between injection logs
Weight, BMI, side effects, meals, macros, coach questions, and engagement tracked over time

Alnu Health platform

One connected layer between patients and care teams.

Alnu pairs a daily patient companion with a clinician portal, turning between-visit activity into structured context that supports more focused, timely care.

01
Daily guidance for patientsInjection tracking, meal analysis, symptom logging, and protocol-aligned coaching.
02
Connected tools for care teamsPatient-level context, population trends, and signals for targeted outreach.
03
Integration-ready infrastructureClinician portal or integration pathways that fit existing workflows.

Product walkthroughs

See the patient experience in action.

Short demonstrations of the core workflows that generate Alnu's structured, longitudinal patient signals.

Nutrition

Photo meal logging

Capture a meal and turn it into structured calorie and macro data.

Nutrition

Nutrition overview

Review meals, macros, and actionable nutrition feedback over time.

Nutrition

Text & voice logging

Log meals flexibly when taking a photo is not the right fit.

Patient journey

Journey overview

Review weight, medication, and progress trends in one place.

Adverse events

Side-effect tracking

Log patient-reported symptoms as structured longitudinal events.

Coach

Personalized coaching

See how patients receive contextual support between clinic visits.

Clinician portal

From individual journeys to population oversight.

Clinician portal

Patient-level view

Daily journey insights surfaced together for the care team.

Clinician portal

Population dashboard

A scalable view of patient health, adherence, trends, and alerts.